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US North America · Source: U.S. Food and Drug Administration (FDA)
Medicine shortages in United States
As of 2 Nov 2026, 1,596 products have a reported shortage in United States, across 165 active ingredients.
Scope: Shortages the FDA lists as current, plus products to be discontinued; one row per package (NDC). Official list.
Products short1,596today
Per million people4.7population ≈ 342 m
Medicines165active ingredients
New in 30 days45reported start
Typical duration3.7 yearsmedian so far
No return date100%of products
When today's shortages began
1,108 started before Dec 2024Current shortages by the month they were reported to start. A tall recent bar means a new wave.
How long they have lasted
When products are expected back
1,596 products have no return date.
Why medicines are short
Which therapeutic classes
Companies with the most products short
Compared with other countries
Registers differ in scope, so treat this as a rough comparison.
Typical duration vs other countries
All 165 medicines short in United States
| Medicine | Products | Earliest start | Latest expected back | Main reason | Countries |
|---|---|---|---|---|---|
| Adalimumab | 6 | 13 Nov 2025 | not given | Not stated | |
| Allopurinol | 4 | 19 Feb 2026 | not given | Not stated | |
| Alteplase | 1 | 21 May 2026 | not given | Not stated | |
| Ampicillin | 5 | 8 Dec 2025 | not given | Not stated | |
| Anagrelide | 2 | 19 Nov 2025 | not given | Not stated | |
| Aprepitant | 1 | 8 Apr 2026 | not given | Not stated | |
| Arsenic Trioxide | 2 | 24 Feb 2026 | not given | Not stated | |
| Atazanavir and Cobicistat | 1 | 3 Nov 2025 | not given | Not stated | |
| Atropine | 19 | 1 Jan 2012 | not given | Not stated | |
| Azacitidine | 9 | 18 Dec 2020 | not given | Not stated | |
| Azithromycin | 3 | 20 Jan 2026 | not given | Not stated | |
| Bupivacaine | 62 | 20 Feb 2018 | not given | Not stated | |
| Calcitriol | 2 | 4 Dec 2025 | not given | Not stated | |
| Carbamazepine | 3 | 19 Dec 2025 | not given | Not stated | |
| Carboplatin | 35 | 28 Apr 2023 | not given | Not stated | |
| Caspofungin | 3 | 12 Jan 2026 | not given | Not stated | |
| Cefepime | 2 | 10 Feb 2026 | not given | Not stated | |
| Cefotaxime | 6 | 17 Feb 2015 | not given | Increased demand | |
| Ceftazidime | 2 | 14 Nov 2025 | not given | Not stated | |
| Cetrorelix | 1 | 13 Nov 2025 | not given | Not stated | |
| Chlorothiazide | 1 | 10 Feb 2026 | not given | Not stated | |
| Cisatracurium | 3 | 6 May 2026 | not given | Not stated | |
| Clindamycin | 22 | 21 Mar 2023 | not given | Not stated | |
| Clindamycin | 6 | 21 Mar 2023 | not given | Not stated | |
| Clonazepam | 40 | 10 Mar 2023 | not given | Not stated | |
| Conivaptan | 1 | 14 Mar 2022 | not given | Distribution or logistics | |
| Dacomitinib | 3 | 8 Jun 2026 | not given | Not stated | |
| Dapsone | 1 | 27 Mar 2026 | not given | Not stated | |
| Daptomycin | 2 | 30 Jun 2026 | not given | Not stated | |
| Decitabine | 2 | 20 Feb 2026 | not given | Not stated | |
| Deferiprone | 1 | 7 Nov 2025 | not given | Not stated | |
| Desflurane | 1 | 2 Jul 2026 | not given | Not stated | |
| Desmopressin | 4 | 12 Mar 2021 | not given | Manufacturing problem | |
| Dexamethasone | 17 | 8 Feb 2019 | not given | Not stated | |
| Dexamethasone | 2 | 8 Feb 2019 | not given | Increased demand | |
| Dexmedetomidine | 60 | 10 Apr 2020 | not given | Not stated | |
| Diclofenac | 6 | 13 Aug 2026 | not given | Not stated | |
| Diltiazem | 1 | 5 Jan 2026 | not given | Not stated | |
| Dobutamine | 10 | 6 Nov 2017 | not given | Not stated | |
| Docetaxel | 2 | 20 Feb 2026 | not given | Not stated | |
| Donepezil and Memantine | 2 | 15 Jun 2026 | not given | Not stated | |
| Dopamine | 11 | 6 Nov 2017 | not given | Not stated | |
| Doxercalciferol | 3 | 10 Dec 2025 | not given | Not stated | |
| Doxycycline | 2 | 30 Jul 2026 | not given | Not stated | |
| Doxycycline | 2 | 12 Jan 2026 | not given | Not stated | |
| Emtricitabine | 2 | 17 Jun 2026 | not given | Not stated | |
| Enoxaparin | 24 | 20 Oct 2026 | not given | Not stated | |
| Epinephrine | 2 | 7 Nov 2025 | not given | Not stated | |
| Etomidate | 18 | 5 Oct 2022 | not given | Not stated | |
| Etravirine | 2 | 28 Apr 2026 | not given | Not stated | |
| Everolimus | 15 | 3 Nov 2025 | not given | Not stated | |
| Fentanyl | 20 | 1 Jan 2012 | not given | Not stated | |
| Fluocinonide | 3 | 2 Oct 2026 | not given | Not stated | |
| Flurazepam | 6 | 3 Aug 2022 | not given | Not stated | |
| Fluvastatin | 3 | 27 Jan 2026 | not given | Not stated | |
| Frovatriptan | 2 | 12 Nov 2025 | not given | Not stated | |
| Fulvestrant | 1 | 14 Aug 2026 | not given | Not stated | |
| Furosemide | 32 | 7 Apr 2020 | not given | Not stated | |
| Gadobutrol | 4 | 30 Jun 2026 | not given | Not stated | |
| Gemfibrozil | 1 | 10 Feb 2026 | not given | Not stated | |
| Glucose | 49 | 13 Jan 2022 | not given | Not stated | |
| Glycerol Phenylbutyrate | 2 | 1 Sep 2026 | not given | Not stated | |
| Glyceryl Trinitrate | 1 | 14 Apr 2026 | not given | Not stated | |
| Guanfacine | 4 | 13 Nov 2025 | not given | Not stated | |
| Haloperidol | 2 | 9 Jan 2026 | not given | Not stated | |
| Heparin | 8 | 14 Nov 2017 | not given | Not stated | |
| Hydralazine | 1 | 7 Apr 2020 | not given | Not stated | |
| Hydrochlorothiazide | 2 | 19 Nov 2025 | not given | Not stated | |
| Hydrocortisone | 2 | 23 Jul 2026 | not given | Not stated | |
| Hydromorphone | 27 | 31 Oct 2017 | not given | Not stated | |
| Hydroxocobalamin | 2 | 4 Nov 2024 | not given | Other | |
| Hydroxychloroquine | 1 | 5 Jan 2026 | not given | Not stated | |
| Icatibant | 2 | 7 May 2026 | not given | Not stated | |
| Idelalisib | 2 | 7 Apr 2026 | not given | Not stated | |
| Ifosfamide | 8 | 12 Jun 2026 | not given | Not stated | |
| Imipenem and Cilastatin | 1 | 8 Jan 2026 | not given | Not stated | |
| Imipenem, Cilastatin and Relebactam | 1 | 9 Sep 2026 | not given | Not stated | |
| Insulin Glargine | 1 | 1 Sep 2026 | not given | Not stated | |
| Insulin Lispro | 2 | 1 Sep 2026 | not given | Not stated | |
| Irinotecan | 2 | 24 Feb 2026 | not given | Not stated | |
| Isocarboxazid | 1 | 16 Apr 2026 | not given | Other | |
| Itraconazole | 3 | 27 Feb 2026 | not given | Not stated | |
| Ivabradine | 3 | 24 Mar 2026 | not given | Not stated | |
| Ivermectin | 1 | 29 Sep 2026 | not given | Not stated | |
| Ketamine | 1 | 7 Nov 2025 | not given | Not stated | |
| Ketorolac | 26 | 23 Mar 2018 | not given | Not stated | |
| Lamivudine | 2 | 19 Oct 2026 | not given | Not stated | |
| Lasmiditan | 6 | 3 Nov 2025 | not given | Not stated | |
| Leflunomide | 3 | 8 Jun 2026 | not given | Not stated | |
| Leflunomide | 2 | 8 Jun 2026 | not given | Not stated | |
| Lidocaine | 49 | 22 Feb 2012 | not given | Not stated | |
| Lidocaine | 18 | 22 Feb 2012 | not given | Not stated | |
| Lincomycin | 3 | 25 Feb 2026 | not given | Not stated | |
| Liraglutide | 11 | 18 Jul 2023 | not given | Not stated | |
| Lisdexamfetamine | 108 | 14 Jul 2023 | not given | Not stated | |
| Lopinavir and Ritonavir | 5 | 24 Jul 2026 | not given | Not stated | |
| Lorazepam | 11 | 3 May 2018 | not given | Increased demand | |
| Lorlatinib | 1 | 15 Jun 2026 | not given | Not stated | |
| Magnesium Pyridoxal 5-Phosphate Glutamate | 1 | 20 Jan 2026 | not given | Not stated | |
| Maraviroc | 1 | 20 Jan 2026 | not given | Not stated | |
| Medroxyprogesterone | 2 | 31 Aug 2026 | not given | Not stated | |
| Melphalan | 1 | 16 Sep 2026 | not given | Not stated | |
| Methotrexate | 15 | 13 Mar 2023 | not given | Not stated | |
| Methylphenidate | 34 | 26 Jul 2023 | not given | Not stated | |
| Methylprednisolone | 22 | 15 Dec 2021 | not given | Not stated | |
| Methylprednisolone | 1 | 16 Jun 2022 | not given | Other | |
| Metoprolol | 7 | 31 Aug 2026 | not given | Not stated | |
| Metronidazole | 3 | 13 Jan 2022 | not given | Not stated | |
| Metronidazole | 1 | 13 Jan 2022 | not given | Other | |
| Micafungin | 2 | 11 Sep 2026 | not given | Not stated | |
| Midazolam | 30 | 2 Apr 2020 | not given | Not stated | |
| Mirikizumab | 2 | 22 Dec 2025 | not given | Not stated | |
| Molnupiravir | 3 | 20 Oct 2026 | not given | Not stated | |
| Montelukast | 1 | 17 Nov 2025 | not given | Not stated | |
| Morphine | 30 | 31 Oct 2017 | not given | Not stated | |
| Nebivolol | 16 | 25 Mar 2026 | not given | Not stated | |
| Nilutamide | 2 | 1 Dec 2025 | not given | Not stated | |
| Nitrofurantoin | 1 | 10 Apr 2026 | not given | Not stated | |
| Oxaliplatin | 4 | 25 Feb 2026 | not given | Not stated | |
| Oxycodone and Paracetamol | 5 | 3 Nov 2025 | not given | Not stated | |
| Palbociclib | 2 | 22 Apr 2026 | not given | Not stated | |
| Palonosetron | 1 | 14 Nov 2025 | not given | Not stated | |
| Palovarotene | 1 | 31 Aug 2026 | not given | Not stated | |
| Pentamidine Isethionate | 1 | 23 Mar 2026 | not given | Not stated | |
| Pentostatin | 1 | 27 Aug 2026 | not given | Other | |
| Phenobarbital | 8 | 31 Oct 2025 | not given | Not stated | |
| Phenoxybenzamine | 3 | 1 Dec 2025 | not given | Not stated | |
| Pindolol | 2 | 30 Jan 2026 | not given | Not stated | |
| Piperacillin and Beta-Lactamase Inhibitor | 1 | 20 Jan 2026 | not given | Not stated | |
| Plerixafor | 1 | 13 Mar 2026 | not given | Not stated | |
| Posaconazole | 1 | 2 Dec 2025 | not given | Not stated | |
| Potassium Chloride | 3 | 21 Nov 2025 | not given | Not stated | |
| Prazosin | 3 | 28 Apr 2023 | not given | Not stated | |
| Progesterone | 1 | 27 Mar 2026 | not given | Not stated | |
| Promethazine | 10 | 21 Nov 2023 | not given | Not stated | |
| Propranolol | 2 | 31 Oct 2023 | not given | Active ingredient shortage | |
| Quinapril | 16 | 19 Jan 2023 | not given | Manufacturing problem | |
| Ramelteon | 2 | 19 Mar 2026 | not given | Not stated | |
| Remifentanil | 9 | 28 Jun 2022 | not given | Not stated | |
| Riluzole | 4 | 26 Jan 2024 | not given | Not stated | |
| Ritonavir | 2 | 24 Jul 2026 | not given | Not stated | |
| Rivaroxaban | 1 | 18 Sep 2026 | not given | Not stated | |
| Rivastigmine | 1 | 18 Sep 2026 | not given | Not stated | |
| Rocuronium Bromide | 26 | 15 Feb 2023 | not given | Not stated | |
| Ropivacaine | 49 | 23 Mar 2018 | not given | Not stated | |
| Saccharated Iron Oxide | 1 | 21 May 2026 | not given | Not stated | |
| Salmeterol and Fluticasone | 3 | 27 Jul 2026 | not given | Not stated | |
| Scopolamine | 1 | 3 Nov 2025 | not given | Not stated | |
| Semaglutide | 3 | 4 Jun 2026 | not given | Not stated | |
| Sodium Acetate | 5 | 3 Feb 2016 | not given | Not stated | |
| Sodium Bicarbonate | 12 | 1 Mar 2017 | not given | Not stated | |
| Sodium Chloride | 3 | 3 Dec 2025 | not given | Not stated | |
| Somatropin | 1 | 14 Nov 2025 | not given | Not stated | |
| Spironolactone | 2 | 10 Dec 2025 | not given | Not stated | |
| Sufentanil | 4 | 3 May 2022 | not given | Other | |
| Sulconazole | 3 | 8 May 2026 | not given | Not stated | |
| Tazemetostat | 1 | 27 Mar 2026 | not given | Not stated | |
| Tiagabine | 4 | 15 Apr 2026 | not given | Not stated | |
| Tobramycin | 1 | 17 Jul 2026 | not given | Not stated | |
| Travoprost | 2 | 7 Jul 2026 | not given | Not stated | |
| Valproic Acid | 2 | 30 Dec 2020 | not given | Increased demand | |
| Valsartan | 4 | 19 Nov 2025 | not given | Not stated | |
| Vancomycin | 1 | 14 Nov 2025 | not given | Not stated | |
| Verapamil | 1 | 21 Nov 2025 | not given | Not stated | |
| Vigabatrin | 1 | 16 Oct 2026 | not given | Not stated |