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ATC L01AA03 · Antineoplastic Agents

Melphalan shortage

As of 31 Oct 2026, Melphalan has a reported shortage in 3 of the 5 countries we track (Germany, Italy, Spain), covering 4 products.

Countries3/5
Products4packs or presentations
Short since9 Sep 20224.1 years ago
Earliest return27 Dec 2026company estimate
No return date1products
Main reasonNot stated

Timeline

GermanyItalySpain
2023202420252026Melphalan-ratiopharm 50 mg Pulver und LösungMelphalan-ratiopharm 50 mg Pulver und Lösungsmittel zur Herstellung einer Injektions- bzw. InfusionslösungMELFALAN SUNMELFALAN SUNMELFALAN TARBIS 50 MG POLVO Y DISOLVENTE PARMELFALAN TARBIS 50 MG POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG, 1 vial de polvo + 1 vial de disolventeMELFALAN ZENTIVA 50 MG POLVO Y DISOLVENTE PAMELFALAN ZENTIVA 50 MG POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG, 1 vial (polvo) + 1 vial de disolventetoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Affected products

CountryProductHolderSinceExpected backReason
DEMelphalan-ratiopharm 50 mg Pulver und Lösungsmittel zur Herstellung einer Injektions- bzw. Infusionslösungratiopharm GmbH5 Jun 202631 Dec 2026Manufacturing problem
Probleme in der Herstellung
ITMELFALAN SUNSUN PHARMACEUTICAL INDUSTRIES (EUROPE) B.V.9 Sep 2022not givenIncreased demand
Elevata richiesta
ESMELFALAN TARBIS 50 MG POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG, 1 vial de polvo + 1 vial de disolventeTarbis Farma S.L.23 Aug 202624 Jan 2027Not stated
ESMELFALAN ZENTIVA 50 MG POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG, 1 vial (polvo) + 1 vial de disolventeZentiva K.S.25 Aug 202627 Dec 2026Not stated

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

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