ATC B01AD02 · Enzymes
Alteplase shortage
As of 2 Nov 2026, Alteplase has a reported shortage in 2 of the 15 countries we track (United States, Canada), covering 2 products from 1 company.
Countries2/15
Products2packs or presentations
Companies11 listed
Short since21 May 20265 months ago
Earliest return31 Jan 2027company estimate
Main reasonNot stated
United States1 product shortCanada1 product shortGermanyNo reported shortageFranceNo reported shortageItalyNo reported shortageSpainNo reported shortageIrelandNo reported shortageAustriaNo reported shortageBelgiumNo reported shortageSwitzerlandNo reported shortageCzechiaNo reported shortageNorwayNo reported shortageSwedenNo reported shortageJapanNo reported shortageAustraliaNo reported shortage
Timeline
United StatesCanada
Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.
Which companies are short
products short, all countriesListed: Roche ROG · SIX Swiss
Compared with similar medicines
ATC group B01AD · EnzymesAffected products
| Country | Product | Company | Since | Expected back | Reason |
|---|---|---|---|---|---|
| US | Activase, Injection, 1 KIT in 1 CARTON (50242-085-27) * 100 mL in 1 VIAL, SINGLE-USE * 100 mL in 1 VIAL, SINGLE USE (NDC 50242-085-27) discontinuation | Genentech, Inc | 21 May 2026 | not given | Not stated |
| CA | ACTIVASE RT-PA (1 x 100mg vial) discontinuation | HOFFMANN-LA ROCHE LIMITED | not given | 31 Jan 2027 | Not stated |
"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.