ATC V03AF01 · Detoxifying Agents for Antineoplastic Treatment · updated 4 Nov 2026
Mesna shortage
As of 4 Nov 2026, Mesna has a reported shortage in 3 of the 16 countries we track (Canada, Italy, Norway), covering 3 products from 1 company.
Is there a Mesna shortage?
Yes. As of 4 Nov 2026, Mesna is reported short in 3 of the 16 countries we track: Canada, Italy, Norway. The earliest expected return is 1 Dec 2026 (Norway). 2 of 3 affected products have no return date. No longer reported short in Germany (since 1 Nov).
How the shortage spread
All cross-border shortagesCountries in the order the shortage started there (earliest start date of a product still short). First reported in Italy on 24 Dec 2025; most recently in Norway on 15 Jun 2026.
Not on the official list in: United States, Germany, France, Spain, Ireland, Austria, Belgium, Switzerland, Czechia, Sweden, Japan, New Zealand, Australia.
Timeline
Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.
Which companies are short
products short, all countriesListed: Baxter BAX · NYSE
Compared with similar medicines
ATC group V03AF · Detoxifying Agents for Antineoplastic TreatmentAffected products
| Country | Product | Company | Since | Expected back | Reason |
|---|---|---|---|---|---|
| CA | UROMITEXAN (10mL Ampoules) | BAXTER CORPORATION | 15 Jun 2026 | not given | Increased demand Demand increase for the drug |
| IT | UROMITEXAN discontinuation | BAXTER S.P.A. | 24 Dec 2025 | not given | Manufacturing problem Problemi produttivi: distribuzione contingentata |
| NO | Uromitexan 400 mg tablett, filmdrasjert, 1 stk endoseblisterpakning | Baxter Medical AB | 15 Jun 2026 | 1 Dec 2026 | Manufacturing problem Produksjonsproblemer |
"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.
Questions
Is there a Mesna shortage?
Yes. As of 4 Nov 2026, Mesna is reported short in 3 of the 16 countries we track: Canada, Italy, Norway. The earliest expected return is 1 Dec 2026 (Norway). 2 of 3 affected products have no return date. No longer reported short in Germany (since 1 Nov).
When will Mesna be back in stock?
Companies expect supply back from 1 Dec 2026 in Norway; Canada: no date given; Italy: no date given; Norway: 1 Dec 2026. These are company estimates reported to each authority.
Why is Mesna in short supply?
The most common reason reported is: manufacturing problem. Reasons by product are listed in the table below.
Which companies have Mesna shortages?
Baxter.