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ATC D04AA10 · Antihistamines for Topical Use · updated 4 Nov 2026

Promethazine shortage

As of 4 Nov 2026, Promethazine has a reported shortage in 1 of the 16 countries we track (United States), covering 10 products from 2 companies.

Is there a Promethazine shortage?

Yes. As of 4 Nov 2026, Promethazine is reported short in 1 of the 16 countries we track: United States. No company has given a return date.

Countries1/16
Products10packs or presentations
Companies21 listed
Short since21 Nov 20233.0 years ago
Earliest returnnot givencompany estimate
Main reasonNot stated
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Timeline

United States
202420252026Phenergan, Injection, 25 mg/1 mL (NDC 0641-6Phenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25)Phenergan, Injection, 25 mg/1 mL (NDC 0641-6Phenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25)Phenergan, Injection, 50 mg/1 mL (NDC 0641-6Phenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25)Phenergan, Injection, 50 mg/1 mL (NDC 0641-6Phenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25)Promethazine Hydrochloride, Injection, 25 mgPromethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25)Promethazine Hydrochloride, Injection, 25 mgPromethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35)Promethazine Hydrochloride, Injection, 25 mgPromethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3)Promethazine Hydrochloride, Injection, 50 mgPromethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25)Promethazine Hydrochloride, Injection, 50 mgPromethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35)Promethazine Hydrochloride, Injection, 50 mgPromethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6)today

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Which companies are short

products short, all countries
Hikma8 HIKXgen Djb2

Listed: Hikma HIK · LSE

Compared with similar medicines

ATC group D04AA · Antihistamines for Topical Use
Dimetindene1/16Promethazine1/16

Affected products

CountryProductCompanySinceExpected backReason
USPhenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenNot stated
USPhenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenOther
USPhenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenNot stated
USPhenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenOther
USPromethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenNot stated
USPromethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenIncreased demand
Demand increase for the drug
USPromethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3)XGen Pharmaceuticals DJB, Inc.21 Nov 2023not givenNot stated
USPromethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenIncreased demand
Demand increase for the drug
USPromethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35)Hikma Pharmaceuticals USA, Inc.21 Nov 2023not givenNot stated
USPromethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6)XGen Pharmaceuticals DJB, Inc.21 Nov 2023not givenIncreased demand
Demand increase for the drug

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Questions

Is there a Promethazine shortage?

Yes. As of 4 Nov 2026, Promethazine is reported short in 1 of the 16 countries we track: United States. No company has given a return date.

When will Promethazine be back in stock?

No return date has been given; United States: no date given. These are company estimates reported to each authority.

Why is Promethazine in short supply?

The most common reason reported is: not stated. Reasons by product are listed in the table below.

Which companies have Promethazine shortages?

Hikma, Xgen Djb.