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ATC S01HA02 · Local Anesthetics · updated 2 Nov 2026

Oxybuprocaine shortage

As of 2 Nov 2026, Oxybuprocaine has a reported shortage in 2 of the 16 countries we track (Italy, Belgium), covering 4 products from 3 companies.

Is there an Oxybuprocaine shortage?

Yes. As of 2 Nov 2026, Oxybuprocaine is reported short in 2 of the 16 countries we track: Italy, Belgium. The earliest expected return is 25 Nov 2026 (Belgium). New since 3 Oct 2026: Belgium.

Countries2/16
Products4packs or presentations
Companies31 listed
Short since30 Sep 202633 days ago
Earliest return25 Nov 2026company estimate
Main reasonManufacturing problem

Timeline

ItalyBelgium
2027Monofree Oxybuprocaine HCl 0.4 % eye drops sMonofree Oxybuprocaine HCl 0.4 % eye drops sol. single-dose cont. 20 x 0.4 ml UDMinims Oxybuprocaine Chlorhydrate 4 mg/ml eyMinims Oxybuprocaine Chlorhydrate 4 mg/ml eye drops sol. single-dose cont. 20 x 0.5 mltoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Which companies are short

products short, all countries
Alfa Intes2Th A1Bausch Health1 BHC

Listed: Bausch Health BHC · NYSE / TSX

Compared with similar medicines

ATC group S01HA · Local Anesthetics
Oxybuprocaine2/16Proxymetacaine2/16Combinations1/16Tetracaine1/16

Affected products

CountryProductCompanySinceExpected backReason
ITBENOXINATO CLORIDRATO INTES anticipatedALFA INTES INDUSTRIA TERAPEUTICA SPLENDORE S.R.L.16 Nov 20261 Feb 2027Manufacturing problem
Problemi produttivi
ITBENOXINATO CLORIDRATO INTES anticipatedALFA INTES INDUSTRIA TERAPEUTICA SPLENDORE S.R.L.22 Dec 20261 Feb 2027Manufacturing problem
Problemi produttivi
BEMonofree Oxybuprocaine HCl 0.4 % eye drops sol. single-dose cont. 20 x 0.4 ml UDLaboratoires Théa30 Sep 20265 Mar 2027Manufacturing problem
Delay in production
BEMinims Oxybuprocaine Chlorhydrate 4 mg/ml eye drops sol. single-dose cont. 20 x 0.5 mlBausch + Lomb Ireland20 Oct 202625 Nov 2026Manufacturing problem
Delay in production

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Questions

Is there an Oxybuprocaine shortage?

Yes. As of 2 Nov 2026, Oxybuprocaine is reported short in 2 of the 16 countries we track: Italy, Belgium. The earliest expected return is 25 Nov 2026 (Belgium). New since 3 Oct 2026: Belgium.

When will Oxybuprocaine be back in stock?

Companies expect supply back from 25 Nov 2026 in Belgium; Italy: 1 Feb 2027; Belgium: 25 Nov 2026. These are company estimates reported to each authority.

Why is Oxybuprocaine in short supply?

The most common reason reported is: manufacturing problem. Reasons by product are listed in the table below.

Which companies have Oxybuprocaine shortages?

Alfa Intes, Th A, Bausch Health.