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IT ATC L04AX03 · updated 2 Nov 2026
Methotrexate shortage in Italy
Is there a Methotrexate shortage in Italy?
Yes. As of 2 Nov 2026, 2 Methotrexate products are reported short in Italy, the first since 31 Aug 2026. No return date has been given. Main reason: manufacturing problem.
Also short in Canada, Germany, Czechia, Sweden, Japan. All countries.
Affected products in Italy
| Country | Product | Company | Since | Expected back | Reason |
|---|---|---|---|---|---|
| IT | METOTREXATO DOC GENERICI | DOC GENERICI SRL | 31 Aug 2026 | not given | Manufacturing problem Problemi produttivi |
| IT | VELOS | DIFA COOPER S.P.A. | 10 Sep 2026 | not given | Increased demand Elevata richiesta/problemi produttivi |
Source
AIFA (Italian Medicines Agency), licensed CC-BY 4.0. Official list. All shortages reported by marketing-authorisation holders, including medicines being withdrawn.