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ATC L04AX03 · Immunosuppressants

Methotrexate shortage

As of 31 Oct 2026, Methotrexate has a reported shortage in 2 of the 5 countries we track (Germany, Italy), covering 3 products.

Countries2/5
Products3packs or presentations
Short since29 Jul 20263 months ago
Earliest return31 Oct 2026company estimate
No return date1products
Main reasonManufacturing problem

Timeline

GermanyItaly
2027Methofill 50 mg/ml Injektionslösung in einerMethofill 50 mg/ml Injektionslösung in einer FertigspritzeMETOTREXATO DOC GENERICIMETOTREXATO DOC GENERICIVELOSVELOStoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Affected products

CountryProductHolderSinceExpected backReason
DEMethofill 50 mg/ml Injektionslösung in einer FertigspritzeAccord Healthcare B.V.29 Jul 202631 Dec 2026Manufacturing problem
Probleme in der Herstellung
ITMETOTREXATO DOC GENERICIDOC GENERICI SRL31 Aug 2026not givenManufacturing problem
Problemi produttivi
ITVELOSDIFA COOPER S.P.A.10 Sep 202631 Oct 2026Increased demand
Elevata richiesta/problemi produttivi

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

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