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ATC V03AB33 · Antidotes · updated 2 Nov 2026

Hydroxocobalamin shortage

As of 2 Nov 2026, Hydroxocobalamin has a reported shortage in 1 of the 16 countries we track (Japan), covering 1 product from 1 company.

Is there a Hydroxocobalamin shortage?

Yes. As of 2 Nov 2026, Hydroxocobalamin is reported short in 1 of the 16 countries we track: Japan. No company has given a return date.

Countries1/16
Products1packs or presentations
Companies10 listed
Short since7 Mar 20242.7 years ago
Earliest returnnot givencompany estimate
Main reasonActive ingredient shortage

Timeline

Japan
202520262027フレスミンS注射液1000μgフレスミンS注射液1000μgtoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Which companies are short

products short, all countries
Yoshindo1

Compared with similar medicines

ATC group V03AB · Antidotes
Sugammadex6/16Thiosulfate4/16Methylthioninium Chloride3/16Naloxone2/16Flumazenil1/16Glutathione1/16Hydroxocobalamin1/16Pralidoxime1/16

Affected products

CountryProductCompanySinceExpected backReason
フレスミンS注射液1000μg limitedYoshindo7 Mar 2024not givenActive ingredient shortage
Raw material (active ingredient) supply problem

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Questions

Is there a Hydroxocobalamin shortage?

Yes. As of 2 Nov 2026, Hydroxocobalamin is reported short in 1 of the 16 countries we track: Japan. No company has given a return date.

When will Hydroxocobalamin be back in stock?

No return date has been given; Japan: no date given. These are company estimates reported to each authority.

Why is Hydroxocobalamin in short supply?

The most common reason reported is: active ingredient shortage. Reasons by product are listed in the table below.

Which companies have Hydroxocobalamin shortages?

Yoshindo.