shortagewatch

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ATC S01XA18 · Other Ophthalmologicals · updated 4 Nov 2026

Ciclosporin shortage

As of 4 Nov 2026, Ciclosporin has a reported shortage in 7 of the 16 countries we track (Canada, Italy, Spain, Austria, Norway, Sweden, Australia), covering 10 products from 2 companies.

Is there a Ciclosporin shortage?

Yes. As of 4 Nov 2026, Ciclosporin is reported short in 7 of the 16 countries we track: Canada, Italy, Spain, Austria, Norway, Sweden, Australia. The earliest expected return is 22 Nov 2026 (Spain). New since 5 Oct 2026: Spain, Norway, Sweden.

Countries7/16
Products10packs or presentations
Companies22 listed
Short since30 Jul 202515 months ago
Earliest return22 Nov 2026company estimate
Main reasonManufacturing problem
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United StatesNo reported shortageCanada1 product shortGermanyNo reported shortageFranceNo reported shortageItaly2 products shortSpain1 product shortIrelandNo reported shortageAustria2 products shortBelgiumNo reported shortageSwitzerlandNo reported shortageCzechiaNo reported shortageNorway1 product shortSweden2 products shortJapanNo reported shortageNew ZealandNo reported shortageAustralia1 product short

How the shortage spread

All cross-border shortages

Countries in the order the shortage started there (earliest start date of a product still short). First reported in Italy on 30 Jul 2025; most recently in Spain on 28 Oct 2026.

Not on the official list in: United States, Germany, France, Ireland, Belgium, Switzerland, Czechia, Japan, New Zealand.

Timeline

CanadaItalySpainAustriaNorwaySwedenAustralia
20262027RESTASIS MULTIDOSE (7 mL)RESTASIS MULTIDOSE (7 mL)IKERVISIKERVISVERKAZIAVERKAZIAIKERVIS 1 mg/ml colirio en emulsion 30 envasIKERVIS 1 mg/ml colirio en emulsion 30 envases unidosis de 0,3 mlIKERVIS 1 mg/ml Augentropfen, Emulsion, 30 SIKERVIS 1 mg/ml Augentropfen, Emulsion, 30 StückVerkazia 1 mg/ml Augentropfen, Emulsion, 120Verkazia 1 mg/ml Augentropfen, Emulsion, 120 StückIkervis 1 mg/ml øyedråper, emulsjon, 30 x 0.Ikervis 1 mg/ml øyedråper, emulsjon, 30 x 0.3 ml endosebeholderIKERVIS 1 mg/ml Endosbehållare, 90 stIKERVIS 1 mg/ml Endosbehållare, 90 stIKERVIS 1 mg/ml Endosbehållare, 30 stIKERVIS 1 mg/ml Endosbehållare, 30 sttoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Which companies are short

products short, all countries
Santen8 4536AbbVie1 ABBV

Listed: AbbVie ABBV · NYSE, Santen 4536 · Tokyo

Compared with similar medicines

ATC group S01XA · Other Ophthalmologicals
Ciclosporin7/16Artificial Tears and Other Indifferent Preparations5/16Acetylcysteine1/16Ascorbic Acid1/16Dexpanthenol1/16Heparin1/16Riboflavin1/16

Affected products

CountryProductCompanySinceExpected backReason
CARESTASIS MULTIDOSE (7 mL)ABBVIE CORPORATION8 Sep 20267 Dec 2026Increased demand
Demand increase for the drug
ITIKERVIS discontinuationSANTEN OY30 Jul 202531 Mar 2027Manufacturing problem
Problemi produttivi (carenza relativa solo al canale retail)
ITVERKAZIASANTEN OY11 Jun 202631 Mar 2027Manufacturing problem
Problemi produttivi
ESIKERVIS 1 mg/ml colirio en emulsion 30 envases unidosis de 0,3 mlSanten Oy28 Oct 202622 Nov 2026Not stated
ATIKERVIS 1 mg/ml Augentropfen, Emulsion, 30 Stück limitedSanten Oy17 Jun 202631 Mar 2027Manufacturing problem
Verzögerung bei der Herstellung
ATVerkazia 1 mg/ml Augentropfen, Emulsion, 120 StückSanten Oy12 Sep 202631 Mar 2027Manufacturing problem
Verzögerung bei der Herstellung
NOIkervis 1 mg/ml øyedråper, emulsjon, 30 x 0.3 ml endosebeholderSanten Oy5 Oct 202631 Dec 2026Manufacturing problem
Produksjonsproblemer
SEIKERVIS 1 mg/ml Endosbehållare, 90 stSanten Oy1 Mar 202631 Dec 2026Not stated
SEIKERVIS 1 mg/ml Endosbehållare, 30 stSanten Oy2 Nov 202631 Dec 2026Not stated
AUIKERVIS ciclosporin 1 mg/mL eye drops emulsion ampoule anticipated23 Jan 202730 Jun 2027Not stated

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Questions

Is there a Ciclosporin shortage?

Yes. As of 4 Nov 2026, Ciclosporin is reported short in 7 of the 16 countries we track: Canada, Italy, Spain, Austria, Norway, Sweden, Australia. The earliest expected return is 22 Nov 2026 (Spain). New since 5 Oct 2026: Spain, Norway, Sweden.

When will Ciclosporin be back in stock?

Companies expect supply back from 22 Nov 2026 in Spain; Canada: 7 Dec 2026; Italy: 31 Mar 2027; Spain: 22 Nov 2026; Austria: 31 Mar 2027; Norway: 31 Dec 2026; Sweden: 31 Dec 2026; Australia: 30 Jun 2027. These are company estimates reported to each authority.

Why is Ciclosporin in short supply?

The most common reason reported is: manufacturing problem. Reasons by product are listed in the table below.

Which companies have Ciclosporin shortages?

Santen, AbbVie.