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ATC D07AA01 · Corticosteroids, Weak (Group I) · updated 4 Nov 2026

Methylprednisolone shortage

As of 4 Nov 2026, Methylprednisolone has a reported shortage in 1 of the 16 countries we track (United States), covering 22 products from 4 companies.

Is there a Methylprednisolone shortage?

Yes. As of 4 Nov 2026, Methylprednisolone is reported short in 1 of the 16 countries we track: United States. No company has given a return date.

Countries1/16
Products22packs or presentations
Companies43 listed
Short since15 Dec 20214.9 years ago
Earliest returnnot givencompany estimate
Main reasonNot stated
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United States22 products shortCanadaNo reported shortageGermanyNo reported shortageFranceNo reported shortageItalyNo reported shortageSpainNo reported shortageIrelandNo reported shortageAustriaNo reported shortageBelgiumNo reported shortageSwitzerlandNo reported shortageCzechiaNo reported shortageNorwayNo reported shortageSwedenNo reported shortageJapanNo reported shortageNew ZealandNo reported shortageAustraliaNo reported shortage

Timeline

United States
20222023202420252026Depo-medrol, Injection, 20 mg/1 mL (NDC 0009Depo-medrol, Injection, 20 mg/1 mL (NDC 0009-0274-01)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-02)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-03)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-51)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-52)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-01)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-03)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-22)Depo-medrol, Injection, 40 mg/1 mL (NDC 0009Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-23)Depo-medrol, Injection, 80 mg/1 mL (NDC 0009Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-02)Depo-medrol, Injection, 80 mg/1 mL (NDC 0009Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-12)Depo-medrol, Injection, 80 mg/1 mL (NDC 0009Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-01)Depo-medrol, Injection, 80 mg/1 mL (NDC 0009Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-03)Methylprednisolone Acetate, Injection, 40 mgMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-05)Methylprednisolone Acetate, Injection, 40 mgMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-10)Methylprednisolone Acetate, Injection, 40 mgMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 55150-313-01)Methylprednisolone Acetate, Injection, 40 mgMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-1)Methylprednisolone Acetate, Injection, 40 mgMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-5)Methylprednisolone Acetate, Injection, 80 mgMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 25021-821-05)Methylprednisolone Acetate, Injection, 80 mgMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 55150-314-01)Methylprednisolone Acetate, Injection, 80 mgMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-1)Methylprednisolone Acetate, Injection, 80 mgMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-5)today

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Which companies are short

products short, all countries
Pfizer13 PFEAmneal4 AMRXSagent3Aurobindo2 AUROPHARMA

Listed: Pfizer PFE · NYSE, Aurobindo AUROPHARMA · NSE, Amneal AMRX · Nasdaq

Affected products

CountryProductCompanySinceExpected backReason
USDepo-medrol, Injection, 20 mg/1 mL (NDC 0009-0274-01)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-02)Pfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-03) limitedPfizer Inc.15 Dec 2021not givenOther
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-51) limitedPfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-52)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-01) limitedPfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-03) limitedPfizer Inc.15 Dec 2021not givenOther
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-22)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-23)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-02)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-12)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-01) limitedPfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-03) limitedPfizer Inc.15 Dec 2021not givenOther
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-05)Sagent Pharmaceuticals15 Dec 2021not givenActive ingredient shortage
Shortage of an active ingredient
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-10) limitedSagent Pharmaceuticals15 Dec 2021not givenActive ingredient shortage
Shortage of an active ingredient
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 55150-313-01)Eugia US LLC15 Dec 2021not givenIncreased demand
Demand increase for the drug
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-1) limitedAmneal Pharmaceuticals15 Dec 2021not givenOther
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-5)Amneal Pharmaceuticals15 Dec 2021not givenNot stated
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 25021-821-05) limitedSagent Pharmaceuticals15 Dec 2021not givenActive ingredient shortage
Shortage of an active ingredient
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 55150-314-01)Eugia US LLC15 Dec 2021not givenIncreased demand
Demand increase for the drug
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-1)Amneal Pharmaceuticals15 Dec 2021not givenNot stated
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-5)Amneal Pharmaceuticals15 Dec 2021not givenNot stated

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Questions

Is there a Methylprednisolone shortage?

Yes. As of 4 Nov 2026, Methylprednisolone is reported short in 1 of the 16 countries we track: United States. No company has given a return date.

When will Methylprednisolone be back in stock?

No return date has been given; United States: no date given. These are company estimates reported to each authority.

Why is Methylprednisolone in short supply?

The most common reason reported is: not stated. Reasons by product are listed in the table below.

Which companies have Methylprednisolone shortages?

Pfizer, Amneal, Sagent, Aurobindo.