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ES ATC L01AA03 · updated 2 Nov 2026

Melphalan shortage in Spain

Is there a Melphalan shortage in Spain?

Yes. As of 2 Nov 2026, 2 Melphalan products are reported short in Spain, the first since 23 Aug 2026. The company estimate for the return is 27 Dec 2026 (latest 24 Jan 2027). Main reason: not stated.

Also short in United States, Germany, Italy. All countries.

Affected products in Spain

CountryProductCompanySinceExpected backReason
ESMELFALAN TARBIS 50 MG POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG, 1 vial de polvo + 1 vial de disolventeTarbis Farma S.L.23 Aug 202624 Jan 2027Not stated
ESMELFALAN ZENTIVA 50 MG POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG, 1 vial (polvo) + 1 vial de disolventeZentiva K.S.25 Aug 202627 Dec 2026Not stated

Source

AEMPS (Spanish Agency of Medicines and Medical Devices), CIMA. Official list. All authorised presentations with a declared supply problem.