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JP ATC N06AA21 · updated 2 Nov 2026
Maprotiline shortage in Japan
Is there a Maprotiline shortage in Japan?
Yes. As of 2 Nov 2026, 4 Maprotiline products are reported short in Japan, the first since 1 Jun 2026. The company estimate for the return is 1 Feb 2027. Main reason: active ingredient shortage.
Also short in France. All countries.
Affected products in Japan
| Country | Product | Company | Since | Expected back | Reason |
|---|---|---|---|---|---|
| JP | マプロチリン塩酸塩錠10mg「アメル」 | Kyowa Pharmaceutical | 1 Jun 2026 | 1 Feb 2027 | Active ingredient shortage Raw material (active ingredient) supply problem |
| JP | マプロチリン塩酸塩錠25mg「アメル」 | Kyowa Pharmaceutical | 1 Jun 2026 | 1 Feb 2027 | Active ingredient shortage Raw material (active ingredient) supply problem |
| JP | ルジオミール錠10mg limited | Sun Pharma | 2 Jun 2026 | not given | Increased demand |
| JP | ルジオミール錠25mg limited | Sun Pharma | 2 Jun 2026 | not given | Increased demand |
Source
MHLW (Ministry of Health, Labour and Welfare), supply status of prescription medicines. Official list. Prescription products under limited shipment or supply suspension (delistings excluded); one row per product.