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ATC B05BC01 · Solutions Producing Osmotic Diuresis · updated 4 Nov 2026

Mannitol shortage

As of 4 Nov 2026, Mannitol has a reported shortage in 2 of the 16 countries we track (Canada, Spain), covering 6 products from 3 companies.

Is there a Mannitol shortage?

Yes. As of 4 Nov 2026, Mannitol is reported short in 2 of the 16 countries we track: Canada, Spain. The earliest expected return is 29 Mar 2027 (Canada). 5 of 6 affected products have no return date. No longer reported short in Czechia (since 2 Nov).

Countries2/16
Products6packs or presentations
Companies32 listed
Short since19 Jan 202522 months ago
Earliest return29 Mar 2027company estimate
Main reasonNot stated
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United StatesNo reported shortageCanada2 products shortGermanyNo reported shortageFranceNo reported shortageItalyNo reported shortageSpain4 products shortIrelandNo reported shortageAustriaNo reported shortageBelgiumNo reported shortageSwitzerlandNo reported shortageCzechiaNo reported shortageNorwayNo reported shortageSwedenNo reported shortageJapanNo reported shortageNew ZealandNo reported shortageAustraliaNo reported shortage

Timeline

CanadaSpain
20262027MANITOL MEIN 10% solución para perfusión, 12MANITOL MEIN 10% solución para perfusión, 12 frascos de 250 mlMANITOL MEIN 20% solución para perfusión, 12MANITOL MEIN 20% solución para perfusión, 12 frascos de 250 mlMANITOL MEIN 10% solución para perfusión, 12MANITOL MEIN 10% solución para perfusión, 12 frascos de 500 mlMANITOL MEIN 20% solución para perfusión, 12MANITOL MEIN 20% solución para perfusión, 12 frascos de 500 mltoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Which companies are short

products short, all countries
Fresenius Kabi4 FREPfizer1 PFEIcu Medical1

Listed: Pfizer PFE · NYSE, Fresenius Kabi FRE · Xetra

Affected products

CountryProductCompanySinceExpected backReason
CAMANNITOL INJECTION USP (25 X 50ML) discontinuationPFIZER CANADA ULCnot given29 Mar 2027Not stated
CAMANNITOL INJECTION USP (500mL) discontinuationICU MEDICAL CANADA INCnot givennot givenNot stated
ESMANITOL MEIN 10% solución para perfusión, 12 frascos de 250 mlFresenius Kabi19 Jan 2025not givenNot stated
ESMANITOL MEIN 20% solución para perfusión, 12 frascos de 250 mlFresenius Kabi8 Apr 2025not givenNot stated
ESMANITOL MEIN 10% solución para perfusión, 12 frascos de 500 mlFresenius Kabi7 Jul 2025not givenNot stated
ESMANITOL MEIN 20% solución para perfusión, 12 frascos de 500 mlFresenius Kabi29 Oct 2025not givenNot stated

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Questions

Is there a Mannitol shortage?

Yes. As of 4 Nov 2026, Mannitol is reported short in 2 of the 16 countries we track: Canada, Spain. The earliest expected return is 29 Mar 2027 (Canada). 5 of 6 affected products have no return date. No longer reported short in Czechia (since 2 Nov).

When will Mannitol be back in stock?

Companies expect supply back from 29 Mar 2027 in Canada; Canada: 29 Mar 2027; Spain: no date given. These are company estimates reported to each authority.

Why is Mannitol in short supply?

The most common reason reported is: not stated. Reasons by product are listed in the table below.

Which companies have Mannitol shortages?

Fresenius Kabi, Pfizer, Icu Medical.