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US ATC N05CD08 · updated 2 Nov 2026
Midazolam shortage in United States
Is there a Midazolam shortage in United States?
Yes. As of 2 Nov 2026, 30 Midazolam products are reported short in United States, the first since 2 Apr 2020. No return date has been given. Main reason: not stated.
Also short in Italy, Ireland, Austria, Belgium, Czechia, Japan. All countries.
Affected products in United States
| Country | Product | Company | Since | Expected back | Reason |
|---|---|---|---|---|---|
| US | Midazolam Hydrochloride Preservative Free, Injection, 10 mg/2 mL (5 mg/mL) (NDC 0409-2308-02) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride Preservative Free, Injection, 2 mg/2 mL (NDC 76045-211-20) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride Preservative Free, Injection, 2 mg/2mL (1 mg/mL) (NDC 0409-0001-25) limited | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride Preservative Free, Injection, 2 mg/2mL (1 mg/mL) (NDC 0409-2305-17) limited | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride Preservative Free, Injection, 5 mg/5 mL (1 mg/mL) (NDC 0409-2305-05) limited | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride Preservative Free, Injection, 5 mg/5 mL (1 mg/mL) Single Dose Glass Fliptop Vial Novaplus (NDC 0409-2305-50) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride Preservative Free, Injection, 5 mg/mL (5 mg/mL) (NDC 0409-2308-01) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride Preservative Free, Injection, 5 mg/mL Single Dose Glass Fliptop Vial Novaplus (NDC 0409-2308-49) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 0641-6056-10) | Hikma Pharmaceuticals USA, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 0641-6057-25) | Hikma Pharmaceuticals USA, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 0641-6059-01) | Hikma Pharmaceuticals USA, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 23155-600-41) | Avet Pharmaceuticals, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 25021-655-02) | Gland Pharma Limited | 2 Apr 2020 | not given | Other |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-411-10) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Distribution or logistics Delay in shipping of the drug |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-411-12) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-411-25) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 10 mg/10 mL (1 mg/mL) (NDC 0409-2587-05) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride, Injection, 10 mg/2 mL (5 mg/mL) Single Dose Glass Fliptop Vial Novaplus (NDC 0409-2308-50) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 25 mg/5 mL (5 mg/mL) (NDC 0409-2596-03) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 0641-6060-10) | Hikma Pharmaceuticals USA, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 0641-6061-25) | Hikma Pharmaceuticals USA, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 23155-601-41) | Avet Pharmaceuticals, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 23155-601-42) | Avet Pharmaceuticals, Inc. | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 25021-661-10) | Gland Pharma Limited | 2 Apr 2020 | not given | Other |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 63323-412-02) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 63323-412-10) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Increased demand Demand increase for the drug |
| US | Midazolam Hydrochloride, Injection, 5 mg/1 mL (NDC 63323-412-25) | Fresenius Kabi USA, LLC | 2 Apr 2020 | not given | Not stated |
| US | Midazolam Hydrochloride, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-2596-05) | Hospira, Inc., a Pfizer Company | 2 Apr 2020 | not given | Not stated |
| US | Midazolam In 0.9% Sodium Chloride, Injection, 1 mg/1 mL (NDC 44567-610-10) | WG Critical Care | 2 Apr 2020 | not given | Not stated |
| US | Midazolam In 0.9% Sodium Chloride, Injection, 1 mg/1 mL (NDC 44567-611-10) | WG Critical Care | 2 Apr 2020 | not given | Not stated |
Source
U.S. Food and Drug Administration (FDA), Drug Shortages via openFDA. Official list. Shortages the FDA lists as current, plus products to be discontinued; one row per package (NDC).