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US ATC D07AA01 · updated 2 Nov 2026

Methylprednisolone shortage in United States

Is there a Methylprednisolone shortage in United States?

Yes. As of 2 Nov 2026, 22 Methylprednisolone products are reported short in United States, the first since 15 Dec 2021. No return date has been given. Main reason: not stated.

Not reported short in any other country we track. All countries.

Affected products in United States

CountryProductCompanySinceExpected backReason
USDepo-medrol, Injection, 20 mg/1 mL (NDC 0009-0274-01)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-02)Pfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-03) limitedPfizer Inc.15 Dec 2021not givenOther
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-51) limitedPfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-52)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-01) limitedPfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-03) limitedPfizer Inc.15 Dec 2021not givenOther
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-22)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-23)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-02)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-12)Pfizer Inc.15 Dec 2021not givenNot stated
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-01) limitedPfizer Inc.15 Dec 2021not givenIncreased demand
Demand increase for the drug
USDepo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-03) limitedPfizer Inc.15 Dec 2021not givenOther
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-05)Sagent Pharmaceuticals15 Dec 2021not givenActive ingredient shortage
Shortage of an active ingredient
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-10) limitedSagent Pharmaceuticals15 Dec 2021not givenActive ingredient shortage
Shortage of an active ingredient
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 55150-313-01)Eugia US LLC15 Dec 2021not givenIncreased demand
Demand increase for the drug
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-1) limitedAmneal Pharmaceuticals15 Dec 2021not givenOther
USMethylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-5)Amneal Pharmaceuticals15 Dec 2021not givenNot stated
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 25021-821-05) limitedSagent Pharmaceuticals15 Dec 2021not givenActive ingredient shortage
Shortage of an active ingredient
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 55150-314-01)Eugia US LLC15 Dec 2021not givenIncreased demand
Demand increase for the drug
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-1)Amneal Pharmaceuticals15 Dec 2021not givenNot stated
USMethylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-5)Amneal Pharmaceuticals15 Dec 2021not givenNot stated

Source

U.S. Food and Drug Administration (FDA), Drug Shortages via openFDA. Official list. Shortages the FDA lists as current, plus products to be discontinued; one row per package (NDC).