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ES ATC L01BA01 · updated 2 Nov 2026

Methotrexate shortage in Spain

Is there a Methotrexate shortage in Spain?

Yes. As of 2 Nov 2026, 2 Methotrexate products are reported short in Spain, the first since 25 Apr 2022. The company estimate for the return is 30 Dec 2026. Main reason: not stated.

Also short in United States, Canada, France, Ireland, Belgium. All countries.

Affected products in Spain

CountryProductCompanySinceExpected backReason
ESMETOTREXATO ACCORD 25 MG/ML SOLUCION INYECTABLE EFG, 1 vial de 20 mlAccord Healthcare S.L.U.25 Apr 202230 Dec 2026Not stated
ESMETOTREXATO ACCORD 25 MG/ML SOLUCION INYECTABLE EFG, 1 vial de 40 mlAccord Healthcare S.L.U.18 Jun 202630 Dec 2026Not stated

Source

AEMPS (Spanish Agency of Medicines and Medical Devices), CIMA. Official list. All authorised presentations with a declared supply problem.